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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484f57388417f8501b5c4215b73b8440a7170602cc9322546bc9a4a5de27af43' 
  AND token = 'bc1iKcFbk1CGyCEDs2tDGo9U4rCdo2KnahdA58NEoKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}