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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1abc7f7fbc5b91e6a4104869aa33505e93e9982200eed6cc1099c5bc2a258834' 
  AND token = 'MYr2MlXgzjy5lsgrrjNaPIPnofY2sVft+pXqeGkZkQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}