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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b0bfe3b5a6812dbedcaea2f7f8b1fb109a7dffbc0da2a9c8bb76ea78de2ea9b' 
  AND token = 'HC+iS45DfAVJEmLkMWggKdVqOXswlDfRZswbtVp88bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}