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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd51af1efe995155d2c53ed93a6722d25ec834bde9fccb8837f9662392aa61199' 
  AND token = 'g1qU5MiTe3YzmIb42TzuKZwHWA2kc5NQVj4/M2XS2hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}