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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afee51f4336e9b98517d09f798317cc9512ec73a28e89e1baa63132a51939c8' 
  AND token = '+p+UsABl7K3wSoxDAoEyxfZx5LeDntALCvNdXe/gugA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}