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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1625a72219d89c7616689c6f31084f229a4b8333f2ede07d157f3957f0b197' 
  AND token = 'RAUYlEs4URz0T4JqHWG1IHJEdFghb0QOcooA6MBzBqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}