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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c921266a2c3bb3ae474761f0542df1d18f1ce9a41ebd3805d6c122d0431f0a' 
  AND token = 'pECLVl3P60mE0hEqm+ILFNEBNMTAx9JJQCzkOaASM4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}