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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464c75f95794c1fd03b8622925fbad14600dde2a90d7a7224f49263a17992997' 
  AND token = '0UEGfk3GzqgM+RFerTemh0ksexsFauJ76EB8noV3zKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}