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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc14459f6e6dc77051b372e59a18e85498cb8e21948522d65d0d49f3ce125bb8' 
  AND token = 'TPPREO0GNxFlc8TarLdqilJAj6CTW+LN46L7mKRYvqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}