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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6f936490098ca5059149c9d869178d563cb560097f2a0b376b8700733c731c' 
  AND token = 'CkO2u3RWT3AlVZFS+I/ha7KLLtztz41YdMAkDR1n1Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}