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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf2279b381d7ca46523cae93cc463202d40e167d4788962df6eee5285862127' 
  AND token = 'WbNeASeEor8HFs5Cu9BI8kB+Sc8I8AKY1/WtZazms/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}