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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2783daf3ecfb27c29c5c322a2cd063b6c50478ce0408a8a056cd3d5b04aebe30' 
  AND token = 'EEUuHMkhocXFp1txQB6faweNQBgDLT3ppOLsOyTCqhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}