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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0a0fc4d937fbc26bf6fdf641bb50a787ab06549c226f2ce5cd47c65fce7cb8' 
  AND token = 'zJrl58dTmxccztnQFJIgCBG0eroZmix38gJA3VK2DQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}