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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8022161748fc6203c38fc77f3cd63071a324c27f52c9489e2688a4120ef8c9ce' 
  AND token = 'VbY/yH+trkmaiPMGSCD+I6IRoXXDDtrOpXkKEWq+JSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}