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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62269068e448fa65e4c162824e22f4054eefb8677f1c5ece93505a408f4a4d01' 
  AND token = 'qnWnn5UsKaH7AOOUVsg9Hty44yeEa9KotXobMOpessM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}