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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5684d822048fc5d551705532bf5f230e2d9920539a95d2e38b7efc3f6884148' 
  AND token = 'yIvI2TZ+uiJmeBlKlSMH5nOFeE0yatOICwGYCl3I3cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}