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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf678f3b593bdee393b9f64f5e032676754d2e1727a7e61a883070722f7718e0' 
  AND token = '98jSeF3u1W1CHgW1RkihoZf473STWs6kimg4bP2JfjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}