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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265829280f98c185df036748b7562ed28b16f2d4f632479836478ef109e48718' 
  AND token = 'NLC2iacczmso2D6qHRzXjvpWtWofsbgAXHXEKo3n2PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}