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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b27728ddf1e3cf7d83e63bb76a40f3c3ed7bdb501387798c95ead869bb436d3' 
  AND token = 'CrO8nQbHPx9zEabl2TBrXcls77SbU7ZC81QSdOSDOg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}