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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ac884f0f46db0a8c2927f40dc0299c8b00e405e39010c9b2776ff7bd0878b5' 
  AND token = 'tTekapsHSJ90QU5BhZSDFlSkm+DiMH0Vn/+QdQochqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}