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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086449ffef13a1b2b8c3586251e55c0290c9e44dd5ae2d06b45aa68485a88224' 
  AND token = 'qrCDWT4JpGpCJ2ew0+kE0QBnbuMLTMmRH0RTjlNKCJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}