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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001ce2ea6c001e809a29f9a8d6b9832262a31cdc0dad3410bdb6f62c353b7409' 
  AND token = 'ggVuHGNne+qxH4Ye2j+UQJ7EsG1s2RgOl1DoSu8srxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}