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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d8771590e4146602aca3eeb0eaacf7f0744d60fe4ed2e4e6b9e43b3a66a59f' 
  AND token = 'AfRJgP05PbWcv+AaJv0bWWjU/6tmlcatW5MyrgzVHe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}