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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86cc0742018daf59102cd88ad424de605e0e8a9061ad8ab4daf1349731d9af4f' 
  AND token = '0WKbqLvp9UgPK12yf36BcafrjljPpVjkXLmdM7yVClw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}