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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54a8398418c1a004a9635f080ca3993d839663873a4235992126751fbefea86' 
  AND token = 'c57rqt6LV351czwyrjvCZo+v/4E50blVnU3Txiulsr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}