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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7e5692c38b19e74397b903e693b58b3f06cb0a16420fb9d83645a3f504f6dc' 
  AND token = 'nqBKJ9EP7SWFee/BtLBWZ9wTyKljizb0nKcamWflRYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}