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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648a6f55d7da7bf49c4dfcc4c675ca7166b3919af1b673c3a908f1e9ba0a1355' 
  AND token = 'MbdQ8Popq/J0ktt7/a5ADFbcRxblEzooPg4zkaogUFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}