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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65def63ffbf4adcd25497692becea8534693e51dc24c6828398324d3969f1e60' 
  AND token = 'fTy+WywaBqRO+3T8rYoqQrBSo7C1ScAaMkf8VjXDcbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}