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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7c66f6986829d94077ca7fed541cc1f2a3660e48ac72328cf9ce01905f4e36' 
  AND token = 'BZPIwSaONDoVwbelrwnOTxO9R9rOr5ZiPln/AQ6uP4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}