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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2e2dda9b34920226357d12a1aaff516a9cc5e400d7ec8a5207736f851a55d9' 
  AND token = 'E9rnpCfgczpaPrgw0t2U4qg0XeSN55kvWmCJ4SWuJp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}