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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded5087446e96da1fb8ad84180ecde9e4f737c56dd40dc584940eb3ff004b840' 
  AND token = 'izUGHRv3QSA+bUSyPRH/i0ymeNF8c3hXjJUhwUc20/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}