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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a70bd27bfe004a379e993916e2fc75834a647952034156f547202e3abf2385' 
  AND token = 'Ne4FsUln4RiUzNyfs9bOvzh2U6MYbZopHtQ/cU+IayI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}