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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d41de717b48b0eb3b400d525c32efd83ba93bc7682377c06151059c05394eea' 
  AND token = 'Ef68Z8XfDwtX46AkPJa5GVeG4l6P7oCQ3MQsLyzZQfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}