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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4daac6e8502476dc37acaf2fd88bf1cb2356a11112885285ef6b58a3f0bb8802' 
  AND token = 'i1yGtURxYLipaqtOqv+K6HJkNqmLLN2qFC6hKt0dtGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}