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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a529e3885d4173dfe3a0a2405d72ed41acd5f0d6ee09d2451f650468a776972' 
  AND token = 'J1oj06Q3wiHmkyztXAu6wmpu47I4LsRyUAoPur+5k5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}