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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff5eb8ce3d06a52f6698db4e35a7c7258d24a80a115426dedda44fd45c3e723' 
  AND token = '4uXHxfMsQcR6R5E39EtxIQXzZIOlLIGR5JUJ9r0KX44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}