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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d853b2a28b708ec19bb7e5613101531e04a2073c68c484d993c8187e956810c' 
  AND token = 'N1hiRQ6Rly2Pht/4R1clqo42gCuaobskFx1Tcd2RlXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}