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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25cf9c1a415a4cd752c78e2d208efe107d5c8d8be71227e14f4d062d1bd8d417' 
  AND token = '6dXhOL7kzPn7TAc8umuUplN4KokYAyC4WZlmZ9nbhks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}