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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6fae1dd550972c25504d6baca5eb008c46553c5f1a12d18a21743aa4102157' 
  AND token = 't6xnzAWnWm1tgoxbmN8D0Z7HwDYHdrRwrCO4tjbbk+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}