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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1856026fbd75b7f0caa156818da079a492a212b75cbaed2579953a2b0c80cc' 
  AND token = 'qe59skEO7Zih4e5c9laJ3xxUNUvSIFHTSR5Ky6N58k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}