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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ee0cccc4ee918eb6932c45f5276e0de52482114fb5faeb05a8f5550921aa5a' 
  AND token = 'mMJwLfpw7pRCaGSHbYwbjlKjhC9qiYNPBLoSzpYrgjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}