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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981c2b810aabafc14f7bb10cacbf9ea6886c84e097337e114b2cf6d4a27d4681' 
  AND token = 'TLlOBiK2XR11gm8ET+PHMNtyl+G+P9vRial2C2BBSUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}