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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f718fc46c255d3880e73200dbcdf75c67f53bd6681bda7537d3e6f18e66d942' 
  AND token = 'D1efulzQgxxyoBLMoZ8dbIL7bW7GBzmuvBHRf8BwXo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}