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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0bdefe35d1d1968939d9d739072c03648702574e260f01ff0cf916b8bb8185b' 
  AND token = '0JEQ4b2HxYlTpmBvdA71laovR8dGrnt0xWJa03emcBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}