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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd4e13acb8413c8fd1eec2c07779a12e0a4f2d18514056952978122c011c2337' 
  AND token = 'ms2PJMF7itUCCOE0TOvNaU0l+Hnmaxp9ruDQ+Y/uE9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}