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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3312fa129c9e0f831345919f9b90c3a6ef2c0ca532e46b03960ce3692499d43' 
  AND token = 's1xLwmSLATMk0axw71/Y8UHB3oTJaaYBC4XXMkKS/aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}