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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7254a088a21499900d9f2d7843935c749f70e28790fd8d20b01c35c33816b90' 
  AND token = '8AORADenarC0vAQtwP94bHpFAaEIHygITQqla+6NsLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}