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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a94d713b16923179fdae0fe5a0f4931b495fa3a66cf8932dad7a8ee1737922' 
  AND token = 'P2W7UGBU++NsPoqRtqa8a5/C6/kpj99o4+fcFTJtGXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}