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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6c7e4f2493b389e4ea3cc58a6c8d225a01d03344d43161b8a7119166601c9a' 
  AND token = 'syeutuplGbhbtngTRBgxX3pK1aMK79aDxB4W7nleIUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}