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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2649677823ec372c9471bfb082383df336ccc0cf2bb331aa5e1d3efdd0fd2327' 
  AND token = 't7ucySXSyWp1SuJIwq+ZF92FYC+XY8JkQgC3EHKp6as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}